Protocol for Chelation

Find a .pdf version of the Protocol for chelating / removing toxic metals from the body.

Additional notes on how to do chelation protocol:

Chelation is an important process of eliminating toxic metals from the body. The process may take from two to twelve months. We will be going through the steps of oral chelation. There are, however, some important tenets to follow:

  1. A high fiber diet is required (see additional notes on diet). In order to eliminate toxins from your system, your body must be maintained in an alkaline state. This may be accomplished by eliminating junk food (sugar, processed food, and refined carbohydrates), red meat, alcohol, etc.
  2. You should have at least 1-3 bowel movements daily. If a problem exists, use stool softeners such as sugar-free Metamucil and One Beyond Fiber.
  3. Drink 3 quarts of water daily to hydrate the system and wash out the toxins.
  4. On the days that you take Chemet (DMSA), finish taking any minerals by 3PM.
  5. Repeat blood work and provocation test every two months.

Steps of oral chelation

  1. DMSA (Chemet) is the main chelating agent that you will use. Take it 3x/week at least 2 hours after dinner (Monday, Wednesday and Friday nights before bedtime). The usual dose is 10mg/kg/dose or 30mg/kg/day (1lb=0.45kg; 1kg=2.2lbs). To minimize side effects, start with 100mg at night and gradually increase to a full dose over a 2-3 week time frame. The most common side effects are gastrointestinal: nausea, diarrhea, loss of appetite, loose stools and/or metallic taste in mouth. There can also be transient liver enzyme elevation. If gastrointestinal symptoms bother you, use Peppermint tea or tablets, or activated charcoal (2-3caps at night). If a rash occurs notify a physician.
  2. L-Glycine is a non-essential amino acid abundantly present in food. Consume 2 hours prior to DMSA. Its role is to transport metals from inside the cells to the outside of the cells where it can be bound by DMSA and removed from the body. The dose is 45mg/kg. Possible contraindications include psychosis, high ammonia levels and/or kidney stones (oxalic acid).
  3. Multivitamins with minerals are essential. We are using a comprehensive mineral/vitamin/amino acid complex called “Doc‘s Best”.
  4. Vitamin C (Ascorbic Acid) reduces toxicity by eliminating multiple toxins, including heavy metals. Vitamin C dosage is calculated by using the Vitamin C flush test (see below).
  5. NAC (N-acetyl-cysteine) increases glutathione body levels. This is the main amino acid helping in detoxification.
  6. Alpha-lipoid acid is a powerful antioxidant that mobilizes heavy metals to enhance the chelation process. It has a protective effect on the nervous system.
  7. Zinc Picolinate increases the body’s production of metallotionen. It protects the kidneys by blocking the absorption of arsenic, cadmium, and mercury. It improves the glutathione level as well.
  8. Magnesium is one of the most deficient nutrients in toxic patients. They tend to excrete high amounts of magnesium. Magnesium is an essential element in over 400 enzymatic body reactions. It is essential for proper liver function activity. We use Magnesium Taurate 125mg capsules (2-3caps, 2x/day). If the dose is too high, the only side effect would be loose bowel movements.
  9. Selenium Picolinate is an essential mineral that increases the glutathione level and reduces toxicity. A deficiency results in chelation side effects.
  10. Liver function and Psyllium are needed to bind toxins in the bowel thus preventing their re-absorption. They also increase hepatic enzyme activity, increase daily fecal bile concentration and excretion, lower cholesterol and lower elevated blood sugar.
  11. Vitamin E 400 IU as mixed tocopherols is an important antioxidant for membrane stabilization. It reduces the body mercury level.
  12. MSM (Methylsulfonylmethane) enhances the liver detoxification process.
  13. Probiotic therapy is important for restoring normal levels of good bacteria in the intestines.
  14. Cilantro is an herb that assists in the mobilization of mercury from the brain.
  15. Garlic is an important herb that restores normal levels of intestinal bacteria and improves chelation. Consume fresh or freeze-dried garlic. Chew parsley to decrease odor.
  16. Uva Ursi 75mg and Marshmallow 75mgs are herbs that protect the kidneys from the heavy metals that are being eliminated.
  17. Copper 1-4mg/day replenishes levels that were chelated and excreted.
  18. Potassium 3000mg (Potassium Citrate aids in mercury removal from the body) has enhancing effects with DMSA and alkalinizes the urine.

Notes: 1×2= 1 cap twice daily; 2×2 = two caps twice daily; 3×2 = 3caps twice daily.

Vitamin C Flush test

We differ in how much Vitamin C (Vit C) or ascorbic acid we need at any given time of our lives. Vit C needs change and vary depending upon our health and nutritional state. If we have a cold, or body toxicity, our Vit C needs are greater than usual. The body has several ways to regulate Vit C levels. The first is the intestinal transport mechanism which limits the amount of Vit C tolerated. The rationale of this mechanism is being used in the Vit C flush test.

It is important to know which type of Vit C is being consumed. Different forms of Vit C are commercially available. Most forms are usually synthetic ascorbic acid. Ascorbic acid comes in 2 forms or polymers: left (L) or right ®. They are look-alike mirror images but only the L polymer is biologically active, i.e. has value for our body functions. The human body can only utilize the L form of ascorbic acid. Unfortunately, most of the commercially sold ascorbic acid does not make a distinction between forms L and R. One company I recommend is Perque Potent C Guard, buffered ascorbate, which uses 100% L-ascorbate. It comes in 2 forms, pill or powder. Powder is easier to absorb, but pills are easier to handle. Vit C is an essential component in the chelation protocol. It is a known free-radical scavenger and has its own chelating properties.

How to do the Vitamin C flush test

Several hours are required for test completion. Plan to have close access to the bathroom throughout testing. It is easier to do the test with the powdered form of buffered Vit C. You will need to keep notes each time you take Vit C. Start the dose on an empty stomach.

Start taking 1/2tsp of Vit C powder diluted in water or juice, every 15 minutes and record the time of each dose. If after 4-5 doses there is no diarrhea, start taking 1 tsp of Vit C powder. When you have repetitive loose bowel movements, your intestines are signaling that they have reached a critical tolerance level of Vit C absorption. Give your body a rest for a few days.

Each tsp contains 3000 mg (3 gms) of Vit C. If you are taking pills, it is easier to dose but takes much longer for absorption and for your body to respond. Your Vit C body requirements can vary between 5ooo mg and 40000 mg.

For the next week or so you will need to take 75% of the achieved dose per day, in divided doses. For example, if you began running to the bathroom after taking 10,000mg Vit C, then your daily dose for the next week should be 7500mg/day divided into 3 doses making it 2500mg/dose. You can ingest the Vit C as pills or dissolved powder. Keep the dissolved powder with water in a dark bottle. Keep refrigerated and sip it all day long.

You may need to repeat the Vit C flush test weekly or every other week. In due time your tolerance will decrease and you will require less dosage.

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